Effect of glucocorticoid therapy on long-term growth and development of children with bronchiolitis / 中国当代儿科杂志

OBJECTIVES@#To explore the effect of glucocorticoid therapy on the growth and development of children with bronchiolitis.@*METHODS@#A total of 143 children with bronchiolitis who were treated with glucocorticoids from February 2017 to March 2018 were enrolled. The medical data were retrospectively collected, including height, weight, course of the disease, and diagnosis and treatment plan at initial admission. After three years of treatment, physical development indices were measured, growth and development were evaluated by Z-score, and related hematological parameters were measured, including osteocalcin, serum phosphorus, and insulin-like growth factor-1.@*RESULTS@#As for the children with bronchiolitis, the incidence rates of growth retardation and obesity increased significantly after three years of glucocorticoid therapy (P<0.05). The children treated with glucocorticoids for ≥29 days showed a significantly higher incidence rate of obesity than those treated with glucocorticoids for <29 days (P<0.05), while nebulized glucocorticoid treatment had no effect on the growth and development (P>0.05). Compared with the children with growth retardation, the children with normal development had significantly higher levels of serum phosphorus and insulin-like growth factor-1 (P<0.05).@*CONCLUSIONS@#Glucocorticoid therapy can adversely affect long-term growth and development in children with bronchiolitis.

Sleep disorders and their influencing factors in primary school children from Urumqi / 中国当代儿科杂志

<p><b>OBJECTIVE</b>To understand the prevalence of sleep disorders and their influencing factors in primary school children from Urumqi.</p><p><b>METHODS</b>A total of 2034 children at the ages of 6-14 years were randomly sampled in 3 districts of Urumqi. The children's sleep states and their family and social environments were investigated through questionnaires.</p><p><b>RESULTS</b>The prevalence of sleep disorders in the subjects was 55%. The prevalence of sleep inquietude was the highest (14.7%), followed by sleep talking (4.8%), sleep walking (1.5%), nocturnal enuresis (1.5%), sleep teeth grinding (5.7%), habitual snoring (12.9%), sleep apnea (0.5%), and waking up by choke (1.9%). Taking drugs to stimulate or inhibit the central nervous system, frequent colds, confined housing area, family history, and sleeping with parents were risk factors for the development of sleep disorders.</p><p><b>CONCLUSIONS</b>The prevalence of sleep disorders within primary school children in Urumqi is higher than the reported data. The development of sleep disorders is multifactorial.</p>